Recombinant Mouse HGF Protein, C-His

Name: Recombinant Mouse HGF Protein, C-His
SKU: PR00127
Availability: InStock

$140.00

Size:10μg

SKU: PR00127-10μg

Catalog No.: PR00127

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product details Specifications Q & A Education

Background:HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. It can also alter epithelium morphology by the induction of nectin‑1 alpha ectodomain shedding, an adhesion protein component of adherens junctions .

Product Overview

Catalog No.: PR00127
SKU: PR00127-10μg
Category: Plasminogen-related growth factor family
Product Type: Other
Size: 10μg/50μg/500μg/1mg
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Research Use Only: Yes

Additional Specifications

Molecule: HGF
Background: HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. It can also alter epithelium morphology by the induction of nectin‑1 alpha ectodomain shedding, an adhesion protein component of adherens junctions .
Species: Mouse
Source: HEK293 Cells
Tags: C-6His
Accession: Q08048
KnownAs: Hepatopoietin-A; Scatter factor; SF; deafness; autosomal recessive 39; DFNB39; F-TCF; hepatocyte growth factor
Protein Length: Gln33-Leu728
Predicted Molecular Mass: 53.5 & 26.9 KDa
N-terminal Sequence: --
SDS-PAGE: 32-38 & 51-59 KDa, reducing conditions
Endotoxin: <0.01 EU/µg as determined by LAL test.
Concentration: --
Purity-SDS-PAGE: >95% as determined by SDS-PAGE.
Purity-SEC-HPLC: --
Activity: --
Form: Lyophilized
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution: Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.