Biotinylated Human TGFB1/TGF-beta-1/LAP Protein, N-Avi

Biotinylated Human TGFB1/TGF-beta-1/LAP Protein, N-Avi
Biotinylated Human TGFB1/TGF-beta-1/LAP Protein, N-Avi
$930.00
Size:20μg
SKU: PR00297-20μg

Catalog No.: PR00297

Specification: 20μg/100μg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product information

Background:Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

Product Overview

Catalog No.
PR00297
SKU
PR00297-20μg
Category
TGF-beta Superfamily
Product Type
Other
Size
20μg/100μg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
TGFB1/TGF-beta-1/LAP
Background
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
Species
Human
Source
HEK293 Cells
Tags
N-Avi
Accession
P01137
KnownAs
Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB
Protein Length
Ala279-Ser390
Predicted Molecular Mass
14.6 KDa
N-terminal Sequence
--
SDS-PAGE
12-18 KDa, reducing conditions
Endotoxin
<0.01 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
--
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH2.5.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:TGF-beta Superfamily