Recombinant Human PDGF-AB Protein

Recombinant Human PDGF-AB Protein
Recombinant Human PDGF-AB Protein
$9,999.00
Size:10μg
SKU: PR00342-10μg

Catalog No.: PR00342

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Platelet-derived growth factor (PDGF) was discovered as a serum-derived component necessary for the growth of smooth muscle cells, fibroblasts, and glial cells. The PDGF family is a product of four gene products and consists of five dimeric isoforms: PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD, and the PDGF-AB heterodimer. These PDGF isoforms produce their cellular effects by specific binding to homodimeric and heterodimeric PDGF receptors. PDGF-AB is an important molecule that regulates the migration and proliferation of different cells, including CRC cells.

Product Overview

Catalog No.
PR00342
SKU
PR00342-10μg
Category
Platelet-derived Growth Factors
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
PDGF-AB
Background
Platelet-derived growth factor (PDGF) was discovered as a serum-derived component necessary for the growth of smooth muscle cells, fibroblasts, and glial cells. The PDGF family is a product of four gene products and consists of five dimeric isoforms: PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD, and the PDGF-AB heterodimer. These PDGF isoforms produce their cellular effects by specific binding to homodimeric and heterodimeric PDGF receptors. PDGF-AB is an important molecule that regulates the migration and proliferation of different cells, including CRC cells.
Species
Human
Source
E. coli
Tags
Tag free
Accession
P04085 & P01127
KnownAs
PDGF-AB
Protein Length
Ser87-Thr211 & Ser82-Thr190
Predicted Molecular Mass
14.1 & 12.4 KDa
N-terminal Sequence
--
SDS-PAGE
(14-16) & (17-19) KDa, reducing conditions
Endotoxin
<0.1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Liquid
Formulation
Supplied as a 0.2 μm filtered solution of 4mM HCl.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
--

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Platelet-derived Growth Factors