- Molecule
- IL18RAP/CD218b
- Background
- IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
- Species
- Human
- Source
- HEK293 Cells
- Tags
- C-Fc-6His
- Accession
- O95256
- KnownAs
- Interleukin-18 receptor accessory protein; IL18RAP;Accessory protein-like; CD218 antigen-like family member B; CDw218b; IL-1R accessory protein-like; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; CD218b; IL1R7
- Protein Length
- Phe20-Arg356
- Predicted Molecular Mass
- 66.4 KDa
- N-terminal Sequence
- --
- SDS-PAGE
- 88 KDa, reducing conditions
- Endotoxin
- <1 EU/µg as determined by LAL test.
- Concentration
- --
- Purity-SDS-PAGE
- >95% as determined by reducing SDS-PAGE.
- Purity-SEC-HPLC
- --
- Activity
- --
- Form
- Lyophilized
- Formulation
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Shipping
- The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.
- Storage
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Please minimize freeze-thaw cycles and use a manual defrost freezer.
- Reconstitution
- Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.