Recombinant Human IL2RB & IL2RG Heterodimer Protein, C-Fc

Recombinant Human IL2RB & IL2RG Heterodimer Protein, C-Fc
Recombinant Human IL2RB & IL2RG Heterodimer Protein, C-Fc
$9,999.00
Size:10μg
SKU: PR02673-10μg

Catalog No.: PR02673

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:The interleukin 2 (IL-2) receptor (IL-2R) is a multisubunit receptor that includes three major IL-2 binding subunits, the IL-2R alpha, beta, and gamma chains. We have detected and analyzed cooperative interactions between the IL-2R alpha and beta chains (IL-2R alpha and IL-2R beta, respectively) in COS cells transfected with cDNAs encoding the IL-2R alpha, the IL-2R beta, or both cDNAs.The affinities of Neo-2/15 for the human and mouse IL-2 receptors (IL-2Rβ and IL-2Rβγc) are significantly higher than those of the corresponding native IL-2 cytokines. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Product Overview

Catalog No.
PR02673
SKU
PR02673-10μg
Category
Interleukins
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
IL2RB & IL2RG Heterodimer
Background
The interleukin 2 (IL-2) receptor (IL-2R) is a multisubunit receptor that includes three major IL-2 binding subunits, the IL-2R alpha, beta, and gamma chains. We have detected and analyzed cooperative interactions between the IL-2R alpha and beta chains (IL-2R alpha and IL-2R beta, respectively) in COS cells transfected with cDNAs encoding the IL-2R alpha, the IL-2R beta, or both cDNAs.The affinities of Neo-2/15 for the human and mouse IL-2 receptors (IL-2Rβ and IL-2Rβγc) are significantly higher than those of the corresponding native IL-2 cytokines. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Species
Human
Source
HEK293 Cells
Tags
C-Fc&C-Fc
Accession
P14784 & P31785
KnownAs
IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG
Protein Length
Ala27-Asp239 & Leu23-Asn254
Predicted Molecular Mass
54 & 51 KDa
N-terminal Sequence
--
SDS-PAGE
(57-72) & (85-115) KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by reducing SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 1 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Interleukins