
Sku: PR17320

Catalog No.: PR02839
Specification: 10μg/50μg/500μg/1mg
Stock: In stock
Product details, specifications, documents, and related products are available from the catalog record. Learn more
Background:The interleukin (IL)-17 cytokine family members IL-17A and IL-17F mediate inflammatory activities via the IL-17 receptor (IL-17R) complex, comprised of the IL-17RA and IL-17RC subunits. IL-17 cytokine family members induce downstream signaling through interactions with a specific cell surface receptor complex. The IL-17 receptor (IL-17R) subfamily includes IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE. The cytoplasmic tail of IL-17RC also contains the conserved SEFIR signaling domain, and IL-17 plays a key role in the development of autoimmunity and inflammation.
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