Recombinant Human IL17RC Protein, C-Flag-Fc

Recombinant Human IL17RC Protein, C-Flag-Fc
Recombinant Human IL17RC Protein, C-Flag-Fc
$9,999.00
Size:10μg
SKU: PR02839-10μg

Catalog No.: PR02839

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product information

Background:The interleukin (IL)-17 cytokine family members IL-17A and IL-17F mediate inflammatory activities via the IL-17 receptor (IL-17R) complex, comprised of the IL-17RA and IL-17RC subunits. IL-17 cytokine family members induce downstream signaling through interactions with a specific cell surface receptor complex. The IL-17 receptor (IL-17R) subfamily includes IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE. The cytoplasmic tail of IL-17RC also contains the conserved SEFIR signaling domain, and IL-17 plays a key role in the development of autoimmunity and inflammation.

Product Overview

Catalog No.
PR02839
SKU
PR02839-10μg
Category
Interleukins
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
IL17RC
Background
The interleukin (IL)-17 cytokine family members IL-17A and IL-17F mediate inflammatory activities via the IL-17 receptor (IL-17R) complex, comprised of the IL-17RA and IL-17RC subunits. IL-17 cytokine family members induce downstream signaling through interactions with a specific cell surface receptor complex. The IL-17 receptor (IL-17R) subfamily includes IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE. The cytoplasmic tail of IL-17RC also contains the conserved SEFIR signaling domain, and IL-17 plays a key role in the development of autoimmunity and inflammation.
Species
Human
Source
HEK293 Cells
Tags
C-Flag-Fc
Accession
NP_703190.2
KnownAs
Interleukin-17 receptor C isoform 1 precursor; IL17RC; IL17-RL; IL17RL; CANDF9; IL17F receptor; IL-17 receptor C; interleukin-17 receptor homolog
Protein Length
Leu21-His465
Predicted Molecular Mass
75 KDa
N-terminal Sequence
--
SDS-PAGE
80-140 KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by reducing SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Interleukins