Recombinant Human IL31RA Protein, C-His

Recombinant Human IL31RA Protein, C-His
Recombinant Human IL31RA Protein, C-His
$9,999.00
Size:10μg
SKU: PR02874-10μg

Catalog No.: PR02874

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:The receptor for IL-31 consists of a heterodimer of IL-31 receptor α-chain (IL-31RA) and oncostatin M receptor β-chain (OSMR β). Intracellular signaling involving binding of the IL-31 receptor by IL-31 is mediated by the Janus kinase (JAK)-signal transducer and activator of transcription (STAT), phosphatidylinositol-3 kinase (PI3K)/AKT (also known as protein kinase B or PKB), and mitogen-activated protein kinase (MAPK) pathways. IL-31RA is expressed by immune cells such as activated macrophages, dendritic cells, eosinophils, and basophils, as well as by epidermal keratinocytes and cutaneous peripheral nerves.

Product Overview

Catalog No.
PR02874
SKU
PR02874-10μg
Category
Interleukins
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
IL31RA
Background
The receptor for IL-31 consists of a heterodimer of IL-31 receptor α-chain (IL-31RA) and oncostatin M receptor β-chain (OSMR β). Intracellular signaling involving binding of the IL-31 receptor by IL-31 is mediated by the Janus kinase (JAK)-signal transducer and activator of transcription (STAT), phosphatidylinositol-3 kinase (PI3K)/AKT (also known as protein kinase B or PKB), and mitogen-activated protein kinase (MAPK) pathways. IL-31RA is expressed by immune cells such as activated macrophages, dendritic cells, eosinophils, and basophils, as well as by epidermal keratinocytes and cutaneous peripheral nerves.
Species
Human
Source
HEK293 Cells
Tags
C-6His
Accession
Q8NI17
KnownAs
IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R (hGLM-R); Gp130-like monocyte receptor (Gp130-like receptor); ZcytoR17; IL31RA
Protein Length
Ala20-Ser516
Predicted Molecular Mass
57.5 KDa
N-terminal Sequence
--
SDS-PAGE
90-130 KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>90% as determined by reducing SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Interleukins