- Molecule
- IL36RN/IL-1F5/IL-36Ra
- Background
- Interleukin 36 receptor antagonist (IL-36RA) is a 16.97 kDa member of IL-1 family with 155 amino acid residues. IL-1RA is expressed by lymphoid tissue, skin and secreted to blood. IL-36Ra functions as a receptor antagonist that inhibits the activation of IL-36R signaling and suppresses pro-inflammatory signaling.
- Species
- Human
- Source
- E. coli
- Tags
- C-6His
- Accession
- Q9UBH0
- KnownAs
- FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1 delta
- Protein Length
- Met1-Asp155
- Predicted Molecular Mass
- 17.77 kDa
- N-terminal Sequence
- --
- SDS-PAGE
- 17 kDa, reducing condition
- Endotoxin
- <0.1 EU/µg as determined by LAL test.
- Concentration
- --
- Purity-SDS-PAGE
- >98% as determined by SDS-PAGE.
- Purity-SEC-HPLC
- --
- Activity
- --
- Form
- Lyophilized
- Formulation
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Shipping
- The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
- Storage
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3-6 months.
Please minimize freeze-thaw cycles and use a manual defrost freezer.
- Reconstitution
- Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL, and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.