- Molecule
- BMP6
- Background
- Bone Morphogenetic Protein-6 (BMP-6) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-6 can bind with the TGF-β receptor and triggers SMAD protein signal transduction. It can keep joint integrity and stability in adults and plays a vital role in regulating hepcidin to maintain iron ions in the body.
- Species
- Human
- Source
- E. coli
- Tags
- C-6His
- Accession
- P22004
- KnownAs
- VGR, VG-1-related protein
- Protein Length
- Val397-His513
- Predicted Molecular Mass
- 14.07 kDa
- N-terminal Sequence
- --
- SDS-PAGE
- 13 kDa, reducing condition
- Endotoxin
- <0.1 EU/µg as determined by LAL test.
- Concentration
- --
- Purity-SDS-PAGE
- >98% as determined by SDS-PAGE.
- Purity-SEC-HPLC
- --
- Activity
- --
- Form
- Lyophilized
- Formulation
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
- Shipping
- The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below.
- Storage
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3-6 months.
Please minimize freeze-thaw cycles and use a manual defrost freezer.
- Reconstitution
- Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL, and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.