- PackSize
- 50ug/100ug
- Target
- Vascular endothelial growth factor A
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A
- Species
- --
- Gene ID-1
- P15692
- Uniprot
- --
- Background
- Suvemcitug is a humanized IgG1κ antibody targeting VEGF derived from the African hare (Oryctolagus cuniculus).<br>• Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy., PMID:12409337<br/>• Vascular endothelial growth factor and its receptors., PMID:7515293<br/>• Tumors: wounds that do not heal-redux., PMID:25568067<br/>• Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis., PMID:12461084<br/>• Differential expression of vascular endothelial growth factor (vascular permeability factor) forms in rat tissues., PMID:8527159<br/>• Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin., PMID:9036922<br/>• Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206., PMID:9529385<br/>• Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney., PMID:9568844<br/>• Proteolytic cleavage of versican and involvement of ADAMTS-1 in VEGF-A/VPF-induced pathological angiogenesis., PMID:21411713<br/>• Isolation and purification of vascular endothelial growth factor (VEGF) from ascitic fluid of ovarian cancer patients., PMID:15188027<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --