- PackSize
- 50ug/100ug
- Target
- A disintegrin and metalloproteinase with thrombospondin m.
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized(Lama/glama)
- Isotype
- VH-VH'
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 5, ADAM-TS5, ADAMTS-5, EC:3.4.24.-, A disintegrin and metalloproteinase with thrombospondin motifs 11, ADAM-TS 11, ADAMTS-11, ADMP-2, Aggrecanase-2, ADAMTS5, ALB, Albumin
- Species
- --
- Gene ID-1
- Q9UNA0 & P02768
- Uniprot
- --
- Background
- Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life.<br>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --