U-Blot® Research Grade Ontuxizumab

Name: U-Blot® Research Grade Ontuxizumab
SKU: WA3291
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3291-50

Catalog No.: WA3291

Specification: 50ug/100ug

Stock: In stock

U-Blot® Research Grade Ontuxizumab Learn more

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U-Blot® Research Grade Ontuxizumab

Product Overview

Catalog No.: WA3291
SKU: WA3291-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: CD164L
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Humanized
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: Endosialin, TEM1, CD164L1, Tumor endothelial marker 1, CD248
Species: --
Gene ID-1: Q9HCU0
Uniprot: --
Background: Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer. • Tumor Endothelial Marker 1 (TEM1/Endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors., PMID:30986375 • TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts., PMID:38254097 • Regulation of matrix reloading by tumor endothelial marker 1 protects against abdominal aortic aneurysm., PMID:39113704 • Role of tumor endothelial marker 1 (Endosialin/CD248) lectin-like domain in lipopolysaccharide-induced macrophage activation and sepsis in mice., PMID:33737161 • Tumor endothelial marker 1 is upregulated in heart after cardiac injury and participates in cardiac remodeling., PMID:35732643 • Preclinical Evaluation and Dosimetry of [111In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1)., PMID:31993928 • Tumor endothelial marker 1-specific DNA vaccination targets tumor vasculature., PMID:24642465 • Endosialin: molecular and functional links to tumor angiogenesis., PMID:26774137 • Endosialin (Tem1) is a marker of tumor-associated myofibroblasts and tumor vessel-associated mural cells., PMID:18187565 • Tumour endothelial marker 1/endosialin-mediated targeting of human sarcoma., PMID:29304474
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.