- PackSize
- 50ug/100ug
- Target
- GLP-1 receptor
- Reactivity
- Human
- Applications
- ELISA, Functional assay, Research in vivo
- Host Species
- --
- Isotype
- Biosynthetic GLP-1 analogs.
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Purified by HPLC.
- Purity
- >95% as determined by HPLC.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Clonality
- --
- Clone Number
- --
- Immunogen
- --
- Alias
- GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R
- Species
- --
- Gene ID-1
- P43220
- Uniprot
- --
- Background
- Liraglutide, 97% similar to native human GLP-1, differs primarily by substituting arginine for lysine at position 34 and involves attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer at the remaining lysine residue at position 26.<br>• The physiology of glucagon-like peptide 1., PMID:17928588<br/>• Glucagon-like peptide-1 receptor: mechanisms and advances in therapy., PMID:39289339<br/>• The structure and function of the glucagon-like peptide-1 receptor and its ligands., PMID:21950636<br/>• Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist., PMID:33177239<br/>• Glucagon-like peptide-1 receptor., PMID:39626623<br/>• Prognostic impact of glucagon-like peptide-1 receptor (GLP1R) expression on cancer survival and its implications for GLP-1R agonist therapy: an integrative analysis across multiple tumor types., PMID:39777709<br/>• Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials., PMID:28244632<br/>• Glucagon-like-peptide 1 receptor agonism and attempted suicide: A Mendelian randomisation study to assess a potential causal association., PMID:38778795<br/>• Glucagon-Like Peptide-1 Receptor Agonism and Suicide Risk: Evidence From Mendelian Randomization., PMID:38879463<br/>• GLP-1, GIP/GLP-1, and GCGR/GLP-1 receptor agonists: Novel therapeutic agents for metabolic dysfunction-associated steatohepatitis., PMID:39735270<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --