- PackSize
- 50ug/100ug
- Target
- G/Glycoprotein
- Reactivity
- Rabies virus (RABV)
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Human
- Isotype
- IgG1, lambda2
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- G, Glycoprotein
- Species
- --
- Gene ID-1
- O92284, P08667
- Uniprot
- --
- Background
- Mazorelvimab (SYN023) is a combination of CTB011 and CTB012 humanized monoclonal antibodies cocktail against rabies virus (RABV). Mezagitamab binds to non-overlapping epitopes on RABV glycoprotein (G). Mezagitamab has potential application in the prevention of rabies.<br>• The glycoprotein G of rhabdoviruses., PMID:7605197<br/>• Chandipura viral glycoprotein (CNV-G) promotes Gectosome generation and enables delivery of intracellular therapeutics., PMID:38702887<br/>• The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism., PMID:32937107<br/>• Viral membrane fusion: is glycoprotein G of rhabdoviruses a representative of a new class of viral fusion proteins?, PMID:15933774<br/>• G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates., PMID:21693135<br/>• Structure and Dynamics of Immunoglobulin G Glycoproteins., PMID:30484251<br/>• Chemical-Synthesis-Based Approach to Glycoprotein Functions in the Endoplasmic Reticulum., PMID:33107166<br/>• Human metapneumovirus glycoprotein G disrupts mitochondrial signaling in airway epithelial cells., PMID:23626834<br/>• Boronic acid functionalized g-C<sub>3</sub>N<sub>4</sub> nanosheets for ultrasensitive and selective sensing of glycoprotein in the physiological environment., PMID:29480294<br/>• 4'-(8-(4-Methylimidazole)-octyloxy)-arctigenin: The first inhibitor of fish rhabdovirus glycoprotein., PMID:37385462<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --