U-Blot® Research Grade Pucotenlimab

Name: U-Blot® Research Grade Pucotenlimab
SKU: WA3397
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3397-50

Catalog No.: WA3397

Specification: 50ug/100ug

Stock: In stock

U-Blot® Research Grade Pucotenlimab Learn more

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U-Blot® Research Grade Pucotenlimab

Product Overview

Catalog No.: WA3397
SKU: WA3397-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: CD1
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Chimeric
Isotype: IgG4-Kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% purity as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Species: --
Gene ID-1: Q15116
Uniprot: --
Background: Balstilimab is a novel, fully human monoclonal immunoglobulin G4 (IgG4) designed to block PD-1 (programmed cell death protein 1) from interacting with its ligands PD-L1 and PD-L2. PD-1 is a negative regulator of immune activation that is considered a foundational target within the immuno-oncology market. • The blockade of immune checkpoints in cancer immunotherapy., PMID:22437870 • PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations., PMID:30888929 • The diverse functions of the PD1 inhibitory pathway., PMID:28990585 • PD-1/PD-L1 immune checkpoint: Potential target for cancer therapy., PMID:30191996 • Immune Checkpoint Blockade in Cancer Therapy., PMID:25605845 • PD-1 expression and clinical PD-1 blockade in B-cell lymphomas., PMID:29118007 • Overcoming T cell exhaustion in infection and cancer., PMID:25797516 • Study and analysis of antitumor resistance mechanism of PD1/PD-L1 immune checkpoint blocker., PMID:32875727 • Tumor Mutational Burden and Response Rate to PD-1 Inhibition., PMID:29262275 • PD-L1., PMID:29097600
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.