U-Blot® Research Grade Vunakizumab

Name: U-Blot® Research Grade Vunakizumab
SKU: WA3807
Availability: InStock

$9,999.00

Size:50ug

SKU: WA3807-50

Catalog No.: WA3807

Specification: 50ug/100ug

Stock: In stock

U-Blot® Research Grade Vunakizumab Learn more

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U-Blot® Research Grade Vunakizumab

Product Overview

Catalog No.: WA3807
SKU: WA3807-50
Category: Biosimilar Antibodies
Product Type: Other
Size: 50ug/100ug
Stock Status: In stock
Available Stock: 999
Minimum Order Quantity: 1

Storage & Compliance

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Research Use Only: Yes

Additional Specifications

PackSize: 50ug/100ug
Target: CTLA-8
Reactivity: Human
Applications: ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host Species: Humanized
Isotype: IgG1-kappa
Conjugate/Modification: --
Recommended Dilution Ratio: --
Composition: 0.01M PBS, pH 7.4.
Purification Process: Protein A/G purified from cell culture supernatant.
Purity: >95% as determined by SDS-PAGE.
storageCondition: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clonality: Monoclonal
Clone Number: --
Immunogen: Mammalian Cells
Alias: CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A
Species: --
Gene ID-1: Q16552
Uniprot: --
Background: Ixekizumab is a humanized monoclonal antibody to interleukin-17A which acts as an antiinflammatory agent and is used to treat moderate-to-severe plaque psoriasis. Ixekizumab has not been linked to serum enzyme elevations during therapy or to instances of idiosyncratic acute liver injury. • The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond., PMID:30127781 • Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability., PMID:26431948 • IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment., PMID:37579542 • The role of IL-17 and anti-IL-17 agents in the immunopathogenesis and management of autoimmune and inflammatory diseases., PMID:34863654 • IL-17 for therapy., PMID:28633806 • Association Between., PMID:35271496 • Vunakizumab: First Approval., PMID:39497021 • The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies., PMID:31278139 • IL-17A Modulates Peritoneal Macrophage Recruitment and M2 Polarization in Endometriosis., PMID:32117261 • Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F., PMID:32973785
Tissue Expression: --
Signaling_pathway: --
Research Areas: --

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

Storage & Handling

Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.