- PackSize
- 50ug/100ug
- Target
- Neurotrophic tyrosine kinase
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-Kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1
- Species
- --
- Gene ID-1
- Q01973
- Uniprot
- --
- Background
- Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.<br>• Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases., PMID:32619402<br/>• SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression., PMID:34599596<br/>• Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors., PMID:7838158<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --