U-Blot® Akt2 Monoclonal Antibody

Name: U-Blot® Akt2 Monoclonal Antibody
SKU: WM0016
Availability: InStock

$268.00

Size:50μL

SKU: WM0016-50

Catalog No.: WM0016

Specification: 50μL/100μL

Stock: In stock

U-Blot® Akt2 Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WM0016
SKU: WM0016-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Akt2
Reactivity: Human,Rat,Monkey
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 56kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of human Akt2 expressed in E. Coli.
Sequence: --
Specificity: Akt2 Monoclonal Antibody detects endogenous levels of Akt2 protein.
Gene Name: AKT2
Protein Name: RAC-beta serine/threonine-protein kinase
Other Name: AKT2;RAC-beta serine/threonine-protein kinase;Protein kinase Akt-2;Protein kinase B beta;PKB beta;RAC-PK-beta
Organism-1: Human
Gene ID-1: 208
SwissProt-1: P31751
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q60823
Organism-3: Rat
Gene ID-3: 25233
SwissProt-3: P47197
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Early endosome . Localizes within both nucleus and cytoplasm of proliferative primary myoblasts and mostly within the nucleus of differentiated primary myoblasts. By virtue of the N-terminal PH domain, is recruited to sites of the plasma membrane containing increased PI(3,4,5)P3 or PI(3,4)P2, cell membrane targeting is also facilitared by interaction with CLIP3. Colocalizes with WDFY2 in early endosomes (By similarity). .