U-Blot® ApoE Monoclonal Antibody

Name: U-Blot® ApoE Monoclonal Antibody
SKU: WM0031
Availability: InStock

$268.00

Size:50μL

SKU: WM0031-50

Catalog No.: WM0031

Specification: 50μL/100μL

Stock: In stock

U-Blot® ApoE Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016],

Product Overview

Catalog No.: WM0031
SKU: WM0031-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: ApoE
Reactivity: Human
Application: WB,IHC,IF,Flow Cyt,ELISA
MW(Calculated): 36kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of human ApoE expressed in E. Coli.
Sequence: --
Specificity: ApoE Monoclonal Antibody detects endogenous levels of ApoE protein.
Gene Name: APOE
Protein Name: Apolipoprotein E
Other Name: APOE;Apolipoprotein E;Apo-E
Organism-1: Human
Gene ID-1: 348
SwissProt-1: P02649
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P08226
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Secreted . Secreted, extracellular space . Secreted, extracellular space, extracellular matrix . In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins (PubMed:1911868, PubMed:8340399). Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans-dependent manner (PubMed:9488694). Lipidation induces the release from the extracellular matrix (PubMed:9488694). .