U-Blot® ARK-1 Monoclonal Antibody

U-Blot® ARK-1 Monoclonal Antibody
U-Blot® ARK-1 Monoclonal Antibody
$268.00
Size:50μL
SKU: WM0038-50

Catalog No.: WM0038

Specification: 50��L/100��L

Stock: In stock

U-Blot® ARK-1 Monoclonal Antibody Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WM0038
SKU
WM0038-50
Category
Mouse mAbs
Product Type
Other
Size
50��L/100��L
Stock Status
In stock
Available Stock
999
Minimum Order Quantity
1

Storage & Compliance

Storage
-15��C to -25��C/1 year(Do not lower than -25��C)
Research Use Only
Yes

Additional Specifications

Target
ARK-1
Reactivity
Human,Rat,Monkey
Application
WB,IHC,IF,ELISA
MW(Calculated)
46kD
MW(Observed)
--
Host Species
Mouse
Isotype
--
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
Affinity purification
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
--
Immunogen
Purified recombinant fragment of human ARK-1 expressed in E. Coli.
Sequence
--
Specificity
ARK-1 Monoclonal Antibody detects endogenous levels of ARK-1 protein.
Gene Name
AURKA
Protein Name
Serine/threonine-protein kinase 6
Other Name
AURKA;AIK;AIRK1;ARK1;AURA;AYK1;BTAK;IAK1;STK15;STK6;Aurora kinase A;Aurora 2;Aurora/IPL1-related kinase 1;ARK-1;Aurora-related kinase 1;hARK1;Breast tumor-amplified kinase;Serine/threonine-protein kinase 15;Serine/threonin
Organism-1
Human
Gene ID-1
6790
SwissProt-1
O14965
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
P97477
Organism-3
Rat
Gene ID-3
--
SwissProt-3
P59241
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, neuron projection . Detected at the neurite hillock in developing neurons (By similarity). Localizes at the centrosome in mitotic cells from early prophase until telophase, but also localizes to the spindle pole MTs from prophase to anaphase (PubMed:9606188, PubMed:17229885, PubMed:21225229). Colocalized with SIRT2 at centrosome (PubMed:22014574). Moves to the midbody during both telophase and cytokinesis (PubMed:17726514). Associates with both the pericentriolar material (PCM) and centrioles (PubMed:22014574). The localization to the spindle poles is regulated by AAAS (PubMed:26246606). .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15��C to -25��C/1 year(Do not lower than -25��C)
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Mouse mAbs