U-Blot® Btk Monoclonal Antibody

U-Blot® Btk Monoclonal Antibody
U-Blot® Btk Monoclonal Antibody
$268.00
Size:50μL
SKU: WM0065-50

Catalog No.: WM0065

Specification: 50μL/100μL

Stock: In stock

U-Blot® Btk Monoclonal Antibody Learn more

1
Share:fx@link

Product information

Product detailsSpecificationsQ & AEducation

Background：The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],

Product Overview

Catalog No.
WM0065
SKU
WM0065-50
Category
Mouse mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Btk
Reactivity
Human,Monkey
Application
WB,IHC,IF,ELISA
MW(Calculated)
76kD
MW(Observed)
--
Host Species
Mouse
Isotype
--
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
Affinity purification
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
--
Immunogen
Purified recombinant fragment of Btk expressed in E. Coli.
Sequence
--
Specificity
Btk Monoclonal Antibody detects endogenous levels of Btk protein.
Gene Name
BTK
Protein Name
Tyrosine-protein kinase BTK
Other Name
BTK;AGMX1;ATK;BPK;Tyrosine-protein kinase BTK;Agammaglobulinaemia tyrosine kinase;ATK;B-cell progenitor kinase;BPK;Bruton tyrosine kinase
Organism-1
Human
Gene ID-1
695
SwissProt-1
Q06187
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
P35991
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. In steady state, BTK is predominantly cytosolic. Following B-cell receptor (BCR) engagement by antigen, translocates to the plasma membrane through its PH domain. Plasma membrane localization is a critical step in the activation of BTK. A fraction of BTK also shuttles between the nucleus and the cytoplasm, and nuclear export is mediated by the nuclear export receptor CRM1.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Request Technical Support
Keywords:Mouse mAbs