U-Blot® eIF4E Monoclonal Antibody

Name: U-Blot® eIF4E Monoclonal Antibody
SKU: WM0154
Availability: InStock

$268.00

Size:50μL

SKU: WM0154-50

Catalog No.: WM0154

Specification: 50μL/100μL

Stock: In stock

U-Blot® eIF4E Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.: WM0154
SKU: WM0154-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: eIF4E
Reactivity: Human
Application: WB,IHC,IF,Flow Cyt,ELISA
MW(Calculated): 25kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of human eIF4E expressed in E. Coli.
Sequence: --
Specificity: eIF4E Monoclonal Antibody detects endogenous levels of eIF4E protein.
Gene Name: EIF4E
Protein Name: Eukaryotic translation initiation factor 4E
Other Name: EIF4E;EIF4EL1;EIF4F;Eukaryotic translation initiation factor 4E;eIF-4E;eIF4E;eIF-4F 25 kDa subunit;mRNA cap-binding protein
Organism-1: Human
Gene ID-1: 1977
SwissProt-1: P06730
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P63073
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, P-body . Cytoplasm . Cytoplasm, Stress granule . Nucleus . Interaction with EIF4ENIF1/4E-T is required for localization to processing bodies (P-bodies) (PubMed:16157702, PubMed:24335285, PubMed:25923732). Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism (PubMed:10856257). .