U-Blot® Fes Monoclonal Antibody

Name: U-Blot® Fes Monoclonal Antibody
SKU: WM0187
Availability: InStock

$268.00

Size:50μL

SKU: WM0187-50

Catalog No.: WM0187

Specification: 50μL/100μL

Stock: In stock

U-Blot® Fes Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009],

Product Overview

Catalog No.: WM0187
SKU: WM0187-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Fes
Reactivity: Human
Application: WB,IHC,IF,ELISA
MW(Calculated): 93kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of Fer expressed in E. Coli.
Sequence: --
Specificity: Fes Monoclonal Antibody detects endogenous levels of Fes protein.
Gene Name: FES
Protein Name: Tyrosine-protein kinase Fes/Fps
Other Name: FES;FPS;Tyrosine-protein kinase Fes/Fps;Feline sarcoma/Fujinami avian sarcoma oncogene homolog;Proto-oncogene c-Fes;Proto-oncogene c-Fps;p93c-fes
Organism-1: Human
Gene ID-1: 2242
SwissProt-1: P07332
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P16879
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Golgi apparatus. Cell junction, focal adhesion. Distributed throughout the cytosol when the kinase is not activated. Association with microtubules requires activation of the kinase activity. Shuttles between focal adhesions and cell-cell contacts in epithelial cells. Recruited to the lateral cell membrane in polarized epithelial cells by interaction with phosphorylated EZR. Detected at tubular membrane structures in the cytoplasm and at the cell periphery.