U-Blot® HAND1 Monoclonal Antibody

Name: U-Blot® HAND1 Monoclonal Antibody
SKU: WM0230
Availability: InStock

$268.00

Size:50μL

SKU: WM0230-50

Catalog No.: WM0230

Specification: 50μL/100μL

Stock: In stock

U-Blot® HAND1 Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WM0230
SKU: WM0230-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HAND1
Reactivity: Human
Application: WB,ELISA
MW(Calculated): 24kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.
Sequence: --
Specificity: HAND1 Monoclonal Antibody detects endogenous levels of HAND1 protein.
Gene Name: HAND1
Protein Name: Heart- and neural crest derivatives-expressed protein 1
Other Name: HAND1;BHLHA27;EHAND;Heart- and neural crest derivatives-expressed protein 1;Class A basic helix-loop-helix protein 27;bHLHa27;Extraembryonic tissues;heart, autonomic nervous system and neural crest derivatives-expressed protein 1;eH
Organism-1: Human
Gene ID-1: 9421
SwissProt-1: O96004
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q64279
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus, nucleoplasm . Nucleus, nucleolus . Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity (By similarity). .