U-Blot® HXK I Monoclonal Antibody

Name: U-Blot® HXK I Monoclonal Antibody
SKU: WM0246
Availability: InStock

$268.00

Size:50μL

SKU: WM0246-50

Catalog No.: WM0246

Specification: 50μL/100μL

Stock: In stock

U-Blot® HXK I Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016],

Product Overview

Catalog No.: WM0246
SKU: WM0246-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HXK I
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,Flow Cyt,ELISA
MW(Calculated): 102kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of human HXK I expressed in E. Coli.
Sequence: --
Specificity: HXK I Monoclonal Antibody detects endogenous levels of HXK I protein.
Gene Name: HK1
Protein Name: Hexokinase-1
Other Name: HK1;Hexokinase-1;Brain form hexokinase;Hexokinase type I;HK I
Organism-1: Human
Gene ID-1: 3098
SwissProt-1: P19367
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P17710
Organism-3: Rat
Gene ID-3: 25058
SwissProt-3: P05708
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). .