U-Blot® IKKε Monoclonal Antibody

U-Blot® IKKε Monoclonal Antibody
U-Blot® IKKε Monoclonal Antibody
$268.00
Size:50μL
SKU: WM0256-50

Catalog No.: WM0256

Specification: 50μL/100μL

Stock: In stock

U-Blot® IKKε Monoclonal Antibody Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009],

Product Overview

Catalog No.
WM0256
SKU
WM0256-50
Category
Mouse mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
IKKε
Reactivity
Human
Application
WB,ELISA
MW(Calculated)
80kD
MW(Observed)
--
Host Species
Mouse
Isotype
--
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
Affinity purification
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
--
Immunogen
Purified recombinant fragment of IKKε (aa1-257) expressed in E. Coli.
Sequence
--
Specificity
IKKε Monoclonal Antibody detects endogenous levels of IKKε protein.
Gene Name
IKBKE
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Other Name
IKBKE;IKKE;IKKI;KIAA0151;Inhibitor of nuclear factor kappa-B kinase subunit epsilon;I-kappa-B kinase epsilon;IKK-E;IKK-epsilon;IkBKE;Inducible I kappa-B kinase;IKK-i
Organism-1
Human
Gene ID-1
9641
SwissProt-1
Q14164
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
Q9R0T8
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Nucleus. Nucleus, PML body . Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent (PubMed:20188669). Located diffusely throughout the cytoplasm but locates to punctate cytoplasmic bodies when coexpressed with TRIM6 (PubMed:24882218). .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Mouse mAbs