
Sku: WM1763R

Catalog No.: WM0269
Specification: 50μL/100μL
Stock: In stock
U-Blot® IRAK-4 Monoclonal Antibody Learn more
Background:This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
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