U-Blot® LIN-28 Monoclonal Antibody

U-Blot® LIN-28 Monoclonal Antibody
U-Blot® LIN-28 Monoclonal Antibody
$268.00
Size:50μL
SKU: WM0298-50

Catalog No.: WM0298

Specification: 50μL/100μL

Stock: In stock

U-Blot® LIN-28 Monoclonal Antibody Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.
WM0298
SKU
WM0298-50
Category
Mouse mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
LIN28A
Reactivity
Human
Application
WB,IF,ELISA
MW(Calculated)
23kD
MW(Observed)
--
Host Species
Mouse
Isotype
--
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
Affinity purification
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
--
Immunogen
Purified recombinant fragment of LIN-28 (aa93-209) expressed in E. Coli.
Sequence
--
Specificity
LIN-28 Monoclonal Antibody detects endogenous levels of LIN-28 protein.
Gene Name
LIN28A
Protein Name
Protein lin-28 homolog A
Other Name
CSDD1;FLJ12457;LIN 28;Lin-28A;LIN28;LIN28A;LN28A_HUMAN;Protein lin-28 homolog A;ZCCHC1;Zinc finger CCHC domain-containing protein 1.
Organism-1
Human
Gene ID-1
79727
SwissProt-1
Q9H9Z2
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
Q8K3Y3
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Rough endoplasmic reticulum . Cytoplasm, P-body . Cytoplasm, Stress granule . Nucleus, nucleolus . Predominantly cytoplasmic (PubMed:22118463). In the cytoplasm, localizes to peri-endoplasmic reticulum regions and detected in the microsomal fraction derived from rough endoplasmic reticulum (RER) following subcellular fractionation. May be bound to the cytosolic surface of RER on which ER-associated mRNAs are translated (By similarity). Shuttle from the nucleus to the cytoplasm requires RNA-binding (PubMed:17617744). Nucleolar localization is observed in 10-15% of the nuclei in differentiated myotubes (By similarity). .

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Mouse mAbs