U-Blot® SOX-2 Monoclonal Antibody

Name: U-Blot® SOX-2 Monoclonal Antibody
SKU: WM0428
Availability: InStock

$268.00

Size:50μL

SKU: WM0428-50

Catalog No.: WM0428

Specification: 50μL/100μL

Stock: In stock

U-Blot® SOX-2 Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：SRY-box 2(SOX2) Homo sapiens This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WM0428
SKU: WM0428-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SOX-2
Reactivity: Human
Application: WB,IHC,IF,ELISA
MW(Calculated): 34kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of human SOX-2 expressed in E. Coli.
Sequence: --
Specificity: SOX-2 Monoclonal Antibody detects endogenous levels of SOX-2 protein.
Gene Name: SOX2
Protein Name: Transcription factor SOX-2
Other Name: SOX2;Transcription factor SOX-2
Organism-1: Human
Gene ID-1: 6657
SwissProt-1: P48431
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P48432
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus speckle . Cytoplasm . Nucleus . Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity). .