U-Blot® TRIM5α Monoclonal Antibody

Name: U-Blot® TRIM5α Monoclonal Antibody
SKU: WM0450
Availability: InStock

$268.00

Size:50μL

SKU: WM0450-50

Catalog No.: WM0450

Specification: 50μL/100μL

Stock: In stock

U-Blot® TRIM5α Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009],

Product Overview

Catalog No.: WM0450
SKU: WM0450-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: TRIM5α
Reactivity: Human
Application: WB,IHC,IF,ELISA
MW(Calculated): 56kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant fragment of human TRIM5α expressed in E. Coli.
Sequence: --
Specificity: TRIM5α Monoclonal Antibody detects endogenous levels of TRIM5α protein.
Gene Name: TRIM5
Protein Name: Tripartite motif-containing protein 5
Other Name: TRIM5;RNF88;Tripartite motif-containing protein 5;RING finger protein 88
Organism-1: Human
Gene ID-1: 85363
SwissProt-1: Q9C035
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Predominantly localizes in cytoplasmic bodies (PubMed:12878161, PubMed:20357094). Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27 (By similarity). In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1 (By similarity). .