U-Blot® HAUSP Monoclonal Antibody

Name: U-Blot® HAUSP Monoclonal Antibody
SKU: WM0492
Availability: InStock

$268.00

Size:50μL

SKU: WM0492-50

Catalog No.: WM0492

Specification: 50μL/100μL

Stock: In stock

U-Blot® HAUSP Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WM0492
SKU: WM0492-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HAUSP
Reactivity: Human,Mouse,Rat,Dog,Pig
Application: WB,IF
MW(Calculated): 128kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human HAUSP (C-terminus) protein fragments expressed in E.coli.
Sequence: --
Specificity: HAUSP Monoclonal Antibody detects endogenous levels of HAUSP protein.
Gene Name: USP7
Protein Name: Ubiquitin carboxyl-terminal hydrolase 7
Other Name: USP7;HAUSP;Ubiquitin carboxyl-terminal hydrolase 7;Deubiquitinating enzyme 7;Herpesvirus-associated ubiquitin-specific protease;Ubiquitin thioesterase 7;Ubiquitin-specific-processing protease 7
Organism-1: Human
Gene ID-1: 7874
SwissProt-1: Q93009
Organism-2: Mouse
Gene ID-2: 252870
SwissProt-2: Q6A4J8
Organism-3: Rat
Gene ID-3: 360471
SwissProt-3: Q4VSI4
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Nucleus, PML body . Chromosome . Present in a minority of ND10 nuclear bodies. Association with ICP0/VMW110 at early times of infection leads to an increased proportion of USP7-containing ND10. Colocalizes with ATXN1 in the nucleus. Colocalized with DAXX in speckled structures. Colocalized with PML and PTEN in promyelocytic leukemia protein (PML) nuclear bodies.