U-Blot® HXK II Monoclonal Antibody

Name: U-Blot® HXK II Monoclonal Antibody
SKU: WM0500
Availability: InStock

$268.00

Size:50μL

SKU: WM0500-50

Catalog No.: WM0500

Specification: 50μL/100μL

Stock: In stock

U-Blot® HXK II Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009],

Product Overview

Catalog No.: WM0500
SKU: WM0500-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HXK II
Reactivity: Human,Mouse,Rat,Pig
Application: WB
MW(Calculated): 102kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-1:2000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human HXK II (N-terminus) protein fragments expressed in E.coli.
Sequence: --
Specificity: HXK II Monoclonal Antibody detects endogenous levels of HXK II protein.
Gene Name: HK2
Protein Name: Hexokinase-2
Other Name: HK2;Hexokinase-2;Hexokinase type II;HK II;Muscle form hexokinase
Organism-1: Human
Gene ID-1: 3099
SwissProt-1: P52789
Organism-2: Mouse
Gene ID-2: 15277
SwissProt-2: O08528
Organism-3: Rat
Gene ID-3: 25059
SwissProt-3: P27881
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175). .