U-Blot® RASSF1 Monoclonal Antibody

Name: U-Blot® RASSF1 Monoclonal Antibody
SKU: WM0531
Availability: InStock

$268.00

Size:50μL

SKU: WM0531-50

Catalog No.: WM0531

Specification: 50μL/100μL

Stock: In stock

U-Blot® RASSF1 Monoclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011],

Product Overview

Catalog No.: WM0531
SKU: WM0531-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RASSF1
Reactivity: Human
Application: WB
MW(Calculated): 39kD
MW(Observed): --
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-1:2000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: Affinity purification
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human RASSF1 protein fragments expressed in E.coli.
Sequence: --
Specificity: RASSF1 Monoclonal Antibody detects endogenous levels of RASSF1 protein.
Gene Name: RASSF1
Protein Name: Ras association domain-containing protein 1
Other Name: RASSF1;RDA32;Ras association domain-containing protein 1
Organism-1: Human
Gene ID-1: 11186
SwissProt-1: Q9NS23
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q99MK9
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform A]: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Nucleus. Localizes to cytoplasmic microtubules during interphase, to bipolar centrosomes associated with microtubules during prophase, to spindle fibers and spindle poles at metaphase and anaphase, to the midzone during early telophase, and to the midbody in late telophase in cells. Colocalizes with MDM2 in the nucleus.; [Isoform C]: Nucleus. Predominantly nuclear.