U-Blot® POU5F1/OCT4 mouse mAb

Name: U-Blot® POU5F1/OCT4 mouse mAb
SKU: WM0566
Availability: InStock

$268.00

Size:50μL

SKU: WM0566-50

Catalog No.: WM0566

Specification: 50μL/100μL

Stock: In stock

U-Blot® POU5F1/OCT4 mouse mAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],

Product Overview

Catalog No.: WM0566
SKU: WM0566-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: POU5F1/OCT4
Reactivity: Mouse
Application: WB
MW(Calculated): --
MW(Observed): 45kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant mouse POU5F1/OCT4 protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of POU5F1/OCT4 and does not cross-react with related proteins.
Gene Name: pou5f1
Protein Name: --
Other Name: MGC22487;Oct 3;Oct 4;Oct-3;Oct-4;OCT3;Oct4;Octamer binding protein 3;Octamer binding protein 4;Octamer binding transcription factor 3;Octamer-binding protein 3;Octamer-binding protein 4;Octamer-binding transcription factor 3;OTF 3;OTF 4;OTF-3;OTF3;OTF4;PO5F1_HUMAN;POU class 5 homeobox 1;POU domain class 5 transcription factor 1;POU domain transcription factor OCT4;POU domain, class 5, transcription factor 1;POU5F1.
Organism-1: Human
Gene ID-1: 18999
SwissProt-1: Q01860
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P20263
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus. .