U-Blot® HAUSP/USP7 mouse mAb

Name: U-Blot® HAUSP/USP7 mouse mAb
SKU: WM0589
Availability: InStock

$268.00

Size:50μL

SKU: WM0589-50

Catalog No.: WM0589

Specification: 50μL/100μL

Stock: In stock

U-Blot® HAUSP/USP7 mouse mAb Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WM0589
SKU: WM0589-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HAUSP/USP7
Reactivity: Human
Application: WB
MW(Calculated): --
MW(Observed): 135kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human HAUSP / USP7 protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of HAUSP / USP7 and does not cross-react with related proteins.
Gene Name: usp7
Protein Name: --
Other Name: USP7;HAUSP;Ubiquitin carboxyl-terminal hydrolase 7;Deubiquitinating enzyme 7;Herpesvirus-associated ubiquitin-specific protease;Ubiquitin thioesterase 7;Ubiquitin-specific-processing protease 7
Organism-1: Human
Gene ID-1: 7874
SwissProt-1: Q93009
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6A4J8
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Nucleus, PML body . Chromosome . Present in a minority of ND10 nuclear bodies. Association with ICP0/VMW110 at early times of infection leads to an increased proportion of USP7-containing ND10. Colocalizes with ATXN1 in the nucleus. Colocalized with DAXX in speckled structures. Colocalized with PML and PTEN in promyelocytic leukemia protein (PML) nuclear bodies.