U-Blot® SIRT6 mouse mAb

Name: U-Blot® SIRT6 mouse mAb
SKU: WM0604
Availability: InStock

$268.00

Size:50μL

SKU: WM0604-50

Catalog No.: WM0604

Specification: 50μL/100μL

Stock: In stock

U-Blot® SIRT6 mouse mAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WM0604
SKU: WM0604-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SIRT6
Reactivity: Human,Mouse,Rat,Monkey
Application: WB,IF,IP
MW(Calculated): --
MW(Observed): 42kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500;IF/ICC1:100
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human SIRT6 protein expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of SIRT6 and does not cross-react with related proteins.
Gene Name: sirt6
Protein Name: --
Other Name: 2810449N18Rik;AI043036;Mono ADP ribosyltransferase sirtuin 6;NAD-dependent protein deacetylase sirtuin-6;Regulatory protein SIR2 homolog 6;Regulatory protein SIR2 homolog;SIR2 like 6;SIR2 like protein 6;Sir2 related protein type 6;SIR2-like protein 6;SIR2
Organism-1: Human
Gene ID-1: 51548
SwissProt-1: Q8N6T7
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P59941
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome . Chromosome, telomere . Endoplasmic reticulum . Predominantly nuclear (PubMed:18337721). Associated with pericentric heterochromatin and telomeric heterochromatin regions (PubMed:18337721, PubMed:27043296). Localizes to DNA damage sites: directly recognizes and binds double-strand breaks (DSBs) sites via a tunnel-like structure that has high affinity for DSBs (PubMed:21680843, PubMed:23911928, PubMed:27568560, PubMed:31995034, PubMed:32538779). A fraction localizes to the endoplasmic reticulum (PubMed:23552949). .