U-Blot® Aurora Kinase A mouse mAb

Name: U-Blot® Aurora Kinase A mouse mAb
SKU: WM0612
Availability: InStock

$268.00

Size:50μL

SKU: WM0612-50

Catalog No.: WM0612

Specification: 50μL/100μL

Stock: In stock

U-Blot® Aurora Kinase A mouse mAb Learn more

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Background：The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WM0612
SKU: WM0612-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Aurora A
Reactivity: Human,Monkey
Application: WB,IF
MW(Calculated): --
MW(Observed): 46kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500;ICC 1:50;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human Aurora Kinase A protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of Aurora Kinase A and does not cross-react with related proteins.
Gene Name: aurka
Protein Name: --
Other Name: AIK;ARK-1;ARK1;AURA;AURKA;Aurora 2;Aurora A;Aurora Family Kinase 1;aurora kinase A;Aurora Related Kinase 1;Aurora-related kinase 1;Aurora/IPL1 Like Kinase;Aurora/IPL1 Related Kinase 1;Aurora/IPL1-related kinase 1;AURORA2;AYK1;BRAK;Breast Tumor Amplified Kinase;Breast tumor-amplified kinase;BTAK;hARK1;IAK;IPL1 Aurora Related Kinase 1;IPL1 Related Kinase;MGC34538;OTTHUMP00000031340;OTTHUMP00000031341;OTTHUMP00000031342;OTTHUMP00000031343;OTTHUMP00000031344;OTTHUMP00000031345;OTTHUMP00000166071;OTTHUMP00000166072;PPP1R47;Protein phosphatase 1, regulatory subunit 47;Serine/threonine kinase 15;Serine/threonine kinase 6;Serine/threonine kinase;Serine/threonine-protein kinase 15;Serine/threonine-protein kinase 6;Serine/threonine-protein kinase aurora-A;STK15;STK6;STK6_HUMAN;STK7.
Organism-1: Human
Gene ID-1: 6790
SwissProt-1: O14965
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P97477
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, neuron projection . Detected at the neurite hillock in developing neurons (By similarity). Localizes at the centrosome in mitotic cells from early prophase until telophase, but also localizes to the spindle pole MTs from prophase to anaphase (PubMed:9606188, PubMed:17229885, PubMed:21225229). Colocalized with SIRT2 at centrosome (PubMed:22014574). Moves to the midbody during both telophase and cytokinesis (PubMed:17726514). Associates with both the pericentriolar material (PCM) and centrioles (PubMed:22014574). The localization to the spindle poles is regulated by AAAS (PubMed:26246606). .