U-Blot® Annexin A1 mouse mAb

Name: U-Blot® Annexin A1 mouse mAb
SKU: WM0725
Availability: InStock

$268.00

Size:50μL

SKU: WM0725-50

Catalog No.: WM0725

Specification: 50μL/100μL

Stock: In stock

U-Blot® Annexin A1 mouse mAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014],

Product Overview

Catalog No.: WM0725
SKU: WM0725-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Annexin I
Reactivity: Human,Mouse,Rat,Monkey
Application: WB
MW(Calculated): --
MW(Observed): 38kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human Annexin A1 beta protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of Annexin A1 and does not cross-react with related proteins.
Gene Name: anxa1
Protein Name: --
Other Name: Annexin 1;Annexin A1;Annexin I;lipocortin I;Annexin I;Annexin-1;AnnexinA1;AnnexinI;ANX 1;ANX A1;ANX1;ANXA 1;ANXA1;ANXA1 protein;ANXA1_HUMAN;Calpactin 2;Calpactin II;Calpactin-2;CalpactinII;Chromobindin 9;Chromobindin-9;Chromobindin9;HGNC:533;Lipocortin 1;Lipocortin I;Lipocortin1;LipocortinI;LPC 1;LPC1;p35;Phospholipase A2 inhibitory protein.
Organism-1: Human
Gene ID-1: 301
SwissProt-1: P04083
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P10107
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Cell projection, cilium . Cell membrane . Membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Basolateral cell membrane . Apical cell membrane . Lateral cell membrane . Secreted . Secreted, extracellular space . Cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted, extracellular exosome . Cytoplasmic vesicle, secretory vesicle lumen . Cell projection, phagocytic cup . Early endosome . Cytoplasmic vesicle membrane ; Peripheral membrane protein . Secreted, at least in part via exosomes and other secretory vesicles. Detected in exosomes and other extracellular vesicles (PubMed:25664854). Alternatively, the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in the protein translocation from the cytoplasm into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). Detected in gelatinase granules in resting neutrophils (PubMed:10772777). Secretion is increased in response to wounding and inflammation (PubMed:25664854). Secretion is increased upon T-cell activation (PubMed:17008549). Neutrophil adhesion to endothelial cells stimulates secretion via gelatinase granules, but foreign particle phagocytosis has no effect (PubMed:10772777). Colocalizes with actin fibers at phagocytic cups (By similarity). Displays calcium-dependent binding to phospholipid membranes (PubMed:2532504, PubMed:8557678). .