U-Blot® SGK1 mouse Monoclonal Antibody(4D12)

U-Blot® SGK1 mouse Monoclonal Antibody(4D12)
U-Blot® SGK1 mouse Monoclonal Antibody(4D12)
$268.00
Size:50μL
SKU: WM1184-50

Catalog No.: WM1184

Specification: 50μL/100μL

Stock: In stock

U-Blot® SGK1 mouse Monoclonal Antibody(4D12) Learn more

Product information

Background:This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009],

Product Overview

Catalog No.
WM1184
SKU
WM1184-50
Category
Mouse mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
SGK1
Reactivity
Human,Rat,Mouse
Application
IHC,IF
MW(Calculated)
--
MW(Observed)
45-60kD
Host Species
Mouse
Isotype
--
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:100-200;IF 1:50-200
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Monoclonal
Clone No.
4D12
Immunogen
Synthetic Peptide of SGK1 at AA range of 350-430
Sequence
--
Specificity
SGK1 protein detects endogenous levels of SGK1
Gene Name
SGK1
Protein Name
SGK1
Other Name
SGK1
Organism-1
Human
Gene ID-1
6446
SwissProt-1
O00141
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
Q9WVC6
Organism-3
Rat
Gene ID-3
--
SwissProt-3
Q06226
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Cell membrane. Mitochondrion. The subcellular localization is controlled by the cell cycle, as well as by exposure to specific hormones and environmental stress stimuli. In proliferating cells, it shuttles between the nucleus and cytoplasm in synchrony with the cell cycle, and in serum/growth factor-stimulated cells it resides in the nucleus. In contrast, after exposure to environmental stress or treatment with glucocorticoids, it is detected in the cytoplasm and with certain stress conditions is associated with the mitochondria. In osmoregulation through the epithelial sodium channel, it can be localized to the cytoplasmic surface of the cell membrane. Nuclear, upon phosphorylation.; [Isoform 2]: Cell membrane.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Mouse mAbs