U-Blot® Beclin-1 mouse Monoclonal Antibody(5C2)

Name: U-Blot® Beclin-1 mouse Monoclonal Antibody(5C2)
SKU: WM1198
Availability: InStock

$268.00

Size:50μL

SKU: WM1198-50

Catalog No.: WM1198

Specification: 50μL/100μL

Stock: In stock

U-Blot® Beclin-1 mouse Monoclonal Antibody(5C2) Learn more

Product details Specifications Q & A Education

Background：beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.: WM1198
SKU: WM1198-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Beclin 1
Reactivity: Human,Rat,Mouse,Bovine
Application: WB,IHC,IF
MW(Calculated): --
MW(Observed): 60kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000;IHC 1:100-200;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Monoclonal
Clone No.: 5C2
Immunogen: Synthetic Peptide of Beclin-1 at AA range of 110-190
Sequence: --
Specificity: Beclin-1 protein detects endogenous levels of BECN1
Gene Name: BECN1
Protein Name: BECN1
Other Name: BECN1
Organism-1: Human
Gene ID-1: 8678
SwissProt-1: Q14457
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: O88597
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q91XJ1
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .