U-Blot® SREBP-1 mouse mAb

Name: U-Blot® SREBP-1 mouse mAb
SKU: WM1256
Availability: InStock

$268.00

Size:50μL

SKU: WM1256-50

Catalog No.: WM1256

Specification: 50μL/100μL

Stock: In stock

U-Blot® SREBP-1 mouse mAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WM1256
SKU: WM1256-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SREBP-1
Reactivity: Human,Mouse,Rat,
Application: WB,IF,ELISA
MW(Calculated): 121kD
MW(Observed): 140kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000;
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: PTR1391
Immunogen: AA range: 1-100
Sequence: --
Specificity: This antibody detects endogenous levels of SREBP-1 protein.
Gene Name: SREBF1 BHLHD1 SREBP1
Protein Name: SREBP-1
Other Name: Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1]
Organism-1: Human
Gene ID-1: 6720
SwissProt-1: P36956
Organism-2: Mouse
Gene ID-2: 20787
SwissProt-2: Q9WTN3
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Membrane