U-Blot® CD117 (C-kit) mouse mAb

Name: U-Blot® CD117 (C-kit) mouse mAb
SKU: WM1466
Availability: InStock

$268.00

Size:50μL

SKU: WM1466-50

Catalog No.: WM1466

Specification: 50μL/100μL

Stock: In stock

U-Blot® CD117 (C-kit) mouse mAb Learn more

Product details Specifications Q & A Education

Background：CD117 is a cell membrane protein encoded by the c-kit proto-oncogene and is a type III transmembrane protein tyrosine kinase growth factor receptor. CD117 is expressed in mast cells, melanocytes and interstitial cells of Cajal. CD117 is positive in 80-100% of gastric stromal sarcoma (GIST). CD117, as a specific marker for immunohistochemical examination of gastric stromal sarcoma (GIST), can be used to clinically guide the personalized target drug (Gleevec) treatment of GIST patients. CD117 can also be used to identify mast cell tumors in lymphoma and as a marker for some testicular germ cell tumors.

Product Overview

Catalog No.: WM1466
SKU: WM1466-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: c-Kit/CD117
Reactivity: Human,
Application: IHC,WB,IF,ELISA
MW(Calculated): 120kD
MW(Observed): 150kD
Host Species: Mouse
Isotype: IgG2b,Kappa
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: Protein G
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: ABT233
Immunogen: Synthesized peptide derived from human CD117 AA range: 300-400
Sequence: --
Specificity: The antibody can specifically recognize human CD117 protein.
Gene Name: KIT SCFR
Protein Name: C Kit;c-Kit;c-Kit Ligand;CD117;Kit;Kit Ligand;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;KIT_HUMAN;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;MGF;p145 c-kit;PBT;Piebald trait protein;Proto oncogene c Kit;Proto oncogene tyrosine protein kinase Kit;Proto-oncogene c-Kit;SCF Receptor;SCFR;soluble KIT variant 1;Steel Factor Receptor;Stem cell factor receptor;tyrosine protein kinase Kit;Tyrosine-protein kinase Kit;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Other Name: C Kit;c-Kit;c-Kit Ligand;CD117;Kit;Kit Ligand;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;KIT_HUMAN;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;MGF;p145 c-kit;PBT;Piebald trait protein;Proto oncogene c Kit;Proto oncogene tyrosine protein kinase Kit;Proto-oncogene c-Kit;SCF Receptor;SCFR;soluble KIT variant 1;Steel Factor Receptor;Stem cell factor receptor;tyrosine protein kinase Kit;Tyrosine-protein kinase Kit;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Organism-1: Human
Gene ID-1: 3815
SwissProt-1: P10721
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P05532
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasmic, Membranous