U-Blot® BOB.1 mouse mAb

Name: U-Blot® BOB.1 mouse mAb
SKU: WM1574
Availability: InStock

$268.00

Size:50μL

SKU: WM1574-50

Catalog No.: WM1574

Specification: 50μL/100μL

Stock: In stock

U-Blot® BOB.1 mouse mAb Learn more

Product details Specifications Q & A Education

Background：disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.,

Product Overview

Catalog No.: WM1574
SKU: WM1574-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: BOB.1
Reactivity: Human,Mouse,
Application: IHC,ELISA
MW(Calculated): 27kD
MW(Observed): 35kD
Host Species: Mouse
Isotype: IgG2a,Kappa
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-200;ELISA 1:500-5000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: ABT-BOB1
Immunogen: Synthesized peptide derived from human BOB.1 AA range: 150-256
Sequence: --
Specificity: The antibody can specifically recognize human BOB.1 protein.
Gene Name: POU2AF1 OBF1
Protein Name: POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)
Other Name: B cell Oct binding protein 1;B cell specific coactivator OBF 1;B cell specific coactivator OBF1;B-cell-specific coactivator OBF-1;BOB 1;BOB-1;OBF 1;OBF1;OBF1_HUMAN;OCA B;OCA-B;OCAB;OCT binding factor 1;OCT-binding factor 1;POU class 2 associating factor 1;POU domain class 2 associating factor 1;POU domain class 2-associating factor 1;Pou2af1
Organism-1: Human
Gene ID-1: 5450
SwissProt-1: Q16633
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nuclear, Cytoplasmic