- Target
- TIM 3
- Reactivity
- Human
- Application
- FC,IF
- MW(Calculated)
- --
- MW(Observed)
- --
- Host Species
- Mouse
- Isotype
- Mouse IgG1/Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
- Form
- PBS, pH 7.4
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Concentration
- 0.5mg/ml
- Clonality
- Monoclonal
- Clone No.
- PTF0116
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- HAVCR2 TIM3 TIMD3
- Protein Name
- Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell membrane protein 3) (TIM-3)
- Other Name
- TIM3;CD366;TIM-3;SPTCL;TIMD3;Tim-3;TIMD-3;HAVcr-2
- Organism-1
- --
- Gene ID-1
- --
- SwissProt-1
- --
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Expressed in T-helper type 1 (Th1) lymphocytes. Expressed on regulatory T (Treg) cells after TCR stimulation. Expressed in dendritic cells and natural killer (NK) cells. Expressed in epithelial tissues. Expression is increased on CD4+ and CD8+ T-cells in chronic hepatitis C virus (HCV) infection. In progressive HIV-1 infection, expression is up-regulated on HIV-1-specific CD8 T-cells.