U-Blot® Recombinant CD26 (VF0392) Fc-Fused Nanobody

Name: U-Blot® Recombinant CD26 (VF0392) Fc-Fused Nanobody
SKU: WN0214
Price: 365 USD
Availability: InStock

$365.00

Size:100μL

SKU: WN0214

Specification: 100μL

Stock: In stock

U-Blot® Recombinant CD26 (VF0392) Fc-Fused Nanobody Learn more

Product details Specifications Q & A Education

Background：CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

Product Overview

Catalog No.: WN0214
SKU: WN0214
Category: Nanobodies
Product Type: Other
Size: 100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Research Use Only: Yes

Additional Specifications

Target: CD184
Reactivity: Human
Application: ELISA
MW(Calculated): --
MW(Observed): --
Host Species: Camel
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: ELISA 1:5000-100000
Form: Phosphate-buffered solution
Source: Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification: Recombinant Expression and Affinity purified
Purity: --
storageCondition: -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration: Please check the information on the tube
Clonality: Monoclonal
Clone No.: PN0339
Immunogen: Purified recombinant Human CD184
Sequence: --
Specificity: This recombinant monoclonal antibody can detects endogenous levels of CD184 protein.
Gene Name: CXCR4
Protein Name: Dipeptidyl peptidase 4 (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]
Other Name: DPP4;ADCP2;CD26;Dipeptidyl peptidase 4;ADABP;Adenosine deaminase complexing protein 2;ADCP-2;Dipeptidyl peptidase IV;DPP IV;T-cell activation antigen CD26;TP103;CD26;CD26 nanobody;
Organism-1: Human
Gene ID-1: 7852
SwissProt-1: P61073
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Cell junction. Early endosome. Late endosome. Lysosome. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC).