
Sku: WN0654

Specification: 100μL
Stock: In stock
U-Blot® Recombinant CD70 (VF0364) Fc-Fused Nanobody Learn more
Background:The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations inThis gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
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