U-Blot® Recombinant IL-6 (VF0598) Fc-Fused Nanobody

Name: U-Blot® Recombinant IL-6 (VF0598) Fc-Fused Nanobody
SKU: WN0639
Price: 365 USD
Availability: InStock

$365.00

Size:100μL

SKU: WN0639

Specification: 100μL

Stock: In stock

U-Blot® Recombinant IL-6 (VF0598) Fc-Fused Nanobody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],

Product Overview

Catalog No.: WN0639
SKU: WN0639
Category: Nanobodies
Product Type: Other
Size: 100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Research Use Only: Yes

Additional Specifications

Target: EGFR
Reactivity: Human
Application: ELISA
MW(Calculated): --
MW(Observed): --
Host Species: Camel
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: ELISA 1:5000-100000
Form: Phosphate-buffered solution
Source: Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification: Recombinant Expression and Affinity purified
Purity: --
storageCondition: -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration: Please check the information on the tube
Clonality: Monoclonal
Clone No.: PN0601
Immunogen: Purified recombinant Human EGFR
Sequence: --
Specificity: This recombinant monoclonal antibody can detects endogenous levels of EGFR protein.
Gene Name: EGFR
Protein Name: Interleukin-6
Other Name: IL6;IFNB2;Interleukin-6;IL-6;B-cell stimulatory factor 2;BSF-2;CTL differentiation factor;CDF;Hybridoma growth factor;Interferon beta-2;IFN-beta-2;IL6 nanobody;
Organism-1: Human
Gene ID-1: 1956
SwissProt-1: P00533
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome . Endosome membrane. Nucleus . In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536, PubMed:17909029). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055). .; [Isoform 2]: Secreted.