U-Blot® Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody

Name: U-Blot® Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody
SKU: WP0088
Availability: InStock

$268.00

Size:50μL

SKU: WP0088-50

Catalog No.: WP0088

Specification: 50μL/100μL

Stock: In stock

U-Blot® Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014],

Product Overview

Catalog No.: WP0088
SKU: WP0088-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Kininogen 1
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 41kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from Cleaved-Kininogen-1 HC (K380) . at AA range: 300-380
Sequence: --
Specificity: Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody detects endogenous levels of fragment of activated Kininogen-1 HC protein resulting from cleavage adjacent to K380.
Gene Name: KNG1
Protein Name: Kininogen-1
Other Name: KNG1;BDK;KNG;Kininogen-1;Alpha-2-thiol proteinase inhibitor;Fitzgerald factor;High molecular weight kininogen;HMWK;Williams-Fitzgerald-Flaujeac factor
Organism-1: Human
Gene ID-1: 3827
SwissProt-1: P01042
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: O08677
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Secreted, extracellular space.