U-Blot® CATB (Cleaved-Leu80) rabbit pAb

Name: U-Blot® CATB (Cleaved-Leu80) rabbit pAb
SKU: WP0110
Availability: InStock

$268.00

Size:50μL

SKU: WP0110-50

Catalog No.: WP0110

Specification: 50μL/100μL

Stock: In stock

U-Blot® CATB (Cleaved-Leu80) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.,function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.,similarity:Belongs to the peptidase C1 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.,

Product Overview

Catalog No.: WP0110
SKU: WP0110-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CATB
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 28kD,37kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000;ELISA 1:5000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human CATB (Cleaved-Leu80)
Sequence: --
Specificity: This antibody detects endogenous levels of Human CATB (Cleaved-Leu80, protein was cleaved amino acid sequence between 79-80)
Gene Name: CTSB CPSB
Protein Name: CATB (Cleaved-Leu80)
Other Name: CTSB;CPSB;Cathepsin B;APP secretase;APPS;Cathepsin B1;[Cleaved into: Cathepsin B light chain;Cathepsin B heavy chain]
Organism-1: Human
Gene ID-1: 1508
SwissProt-1: P07858
Organism-2: Mouse
Gene ID-2: 13030
SwissProt-2: P10605
Organism-3: Rat
Gene ID-3: --
SwissProt-3: P00787
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Lysosome . Melanosome . Secreted, extracellular space . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells (By similarity). .