U-Blot® CATL1 (heavy chain, Cleaved-Ala114) rabbit pAb

Name: U-Blot® CATL1 (heavy chain, Cleaved-Ala114) rabbit pAb
SKU: WP0114
Availability: InStock

$268.00

Size:50μL

SKU: WP0114-50

Catalog No.: WP0114

Specification: 50μL/100μL

Stock: In stock

U-Blot® CATL1 (heavy chain, Cleaved-Ala114) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,

Product Overview

Catalog No.: WP0114
SKU: WP0114-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Cathepsin L
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 25kD,37kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000;ELISA 1:5000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human CATL1 (heavy chain, Cleaved-Ala114)
Sequence: --
Specificity: This antibody detects endogenous levels of Human CATL1 (heavy chain, Cleaved-Ala114, protein was cleaved amino acid sequence between 113-114 )
Gene Name: CTSL1 CTSL
Protein Name: CATL1 (heavy chain, Cleaved-Ala114)
Other Name: Cathepsin L1;Major excreted protein;MEP;[Cleaved into: Cathepsin L1 heavy chain;Cathepsin L1 light chain]
Organism-1: Human
Gene ID-1: 1514
SwissProt-1: P07711
Organism-2: Mouse
Gene ID-2: 13039
SwissProt-2: P06797
Organism-3: Rat
Gene ID-3: 25697
SwissProt-3: P07154
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Lysosome . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Cytoplasmic vesicle, secretory vesicle, chromaffin granule . Secreted, extracellular space . Secreted . Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages. .; [Isoform 2]: Nucleus . Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and do not transit through the endoplasmic reticulum to localize to the nucleus (PubMed:15099520). Nuclear location varies during the cell cycle, with higher levels during S phase (PubMed:15099520). .